Cirrhosis

Cirrhosis is a chronic liver disease characterized by the progressive scarring and fibrosis of liver tissue, leading to impaired liver function. This condition can result from various factors, including chronic alcohol abuse, viral hepatitis infections (such as hepatitis B and C), non-alcoholic fatty liver disease (NAFLD), autoimmune hepatitis, and certain genetic disorders. As cirrhosis advances, the liver's ability to perform vital functions such as detoxification, protein synthesis, and bile production becomes compromised. Patients with cirrhosis may experience symptoms such as fatigue, jaundice, abdominal swelling (ascites), easy bruising or bleeding, and mental confusion (hepatic encephalopathy). Complications of cirrhosis can be severe and life-threatening, including portal hypertension, which can lead to variceal bleeding and ascites, hepatorenal syndrome, liver cancer (hepatocellular carcinoma), and liver failure. Diagnosis of cirrhosis is typically made based on clinical evaluation, laboratory tests (such as liver function tests), imaging studies (such as ultrasound or MRI), and sometimes liver biopsy. Management of cirrhosis aims to slow disease progression, alleviate symptoms, and prevent complications. This may involve lifestyle modifications (such as alcohol cessation and dietary changes), medications to manage symptoms and complications, regular surveillance for liver cancer, and in some cases, liver transplantation for end-stage liver disease. Early diagnosis and intervention are crucial in managing cirrhosis and improving patient outcomes, emphasizing the importance of regular medical monitoring and adherence to treatment plans.

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